Pharmacokinetics of intravenous clomiphene isomers.

Pharmacokinetics of Cefepime Following Intravenous and Intramuscular Administration in Sheep

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Pharmacokinetics of tetracycline hydrochloride after single intravenous injection in dogs

Six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. Blood samples were collected before and at various time intervals after the administration of the drug. Serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. Non...

The Isomers of Clomiphene Citrate have Dissimilar Dispositions Once Ingested: Results of a Mouse ADME Study

Background: Clomiphene Citrate is composed of two structural isomers: cisor Zuclomiphene citrate (Zu) and transor Enclomiphene citrate (En). Clomiphene, as well as isolate isomers, has recently been shown to have effects on Ebola virus infections. It has been shown that the enclomiphene molecule is an estrogen antagonist and that zuclomiphene is inactive. We demonstrate here that the two isomer...

Pharmacokinetics of intravenous ketorolac following caesarean delivery.

BACKGROUND Drug disposition is altered by pregnancy and the peripartum period but data on intravenous ketorolac pharmacokinetics following caesarean delivery have not been previously reported. METHODS At the end of caesarean delivery, women received an intravenous bolus of ketorolac tromethamine 30 mg (immediate postpartum, Group IP). Plasma samples were collected at 1, 2, 4, 6 and 8h. A simi...

Title:covariates of Intravenous Paracetamol Pharmacokinetics in Adults